Endocrine Abstracts

A 57-year-old man presented with a 6-month history of worsening headaches and bitemporal hemianopia on visual field examination. MRI of the brain revealed a 3 cm pituitary lesion impinging the optic chiasm and indenting the pons. Appearances of the lesion on imaging and the patient’s normal anterior pituitary hormonal profile were highly suggestive of a non-functioning pituitary adenoma and this was the presumed diagnosis. The patient underwent trans-sphenoidal resection ...

In 2008, we presented data showing that combining sonography and scintigraphy investigations resulted in the correct identification of a parathyroid adenoma in 97% (28/29) patients undergoing parathyroid surgery for primary hyperparathyroidism (PHPT). Further to this audit we compared the treatment of PHPT against the standards set by NIH in 2008. All patients who had Setamibi +/ ultrasound scan over 18 month (July 2006 until December 2007) for biochemically confirmed PHPT wer...

Background and aims: It is well known that most of the pregnancy complications (maternal, fetal, & neonatal) increased noticeably in diabetic pregnancy compared with non diabetics, our aims of this study is the impact of the type of diabetes in pregnancy upon pregnancy outcome.Methods: This is a crosse study analyzed 210 pregnant women who are undergoing antenatal follow up in diabetic pregnancy clinic, and then delivered in Aljalaa Maternity Hospita...

Aims: To determine whether single parenthood, special needs, ethnicity and indices of multiple deprivation 2007(proxy for social deprivation) influence metabolic control in T1DM.Methodology: Retrospective study (12 months) from 01/01/2007 till 31/12/2007. Data on several demographic and clinical variables were obtained from 105 children with T1DM from a single centre, after applying explicit exclusion criteria. Glycaemic control was assessed using HbA1c ...

Background: There is controversy about the ideal outcome for radio-active iodine (RAI) treatment in thyrotoxicosis and the optimal dose to be given. Various centres use various doses ranging from 185 mBq to 550 mBq.Aim: Our aim was to determine the thyroid status post RAI treatment for thyrotoxicosis and in those who became hypothyroid, to assess the time of onset of hypothyroidism from the date of RAI treatment administration.Meth...

We presenting a case of 26 old lady who is known to have Denys-Drash syndrome, epilepsy and bronchial asthma who presented with history of recent significant weight gain, extensive abdominal bruising and significant muscle weakness which she described literally as not able to use her upper limbs to move to help shuffle her bottom in the floor, a manoeuvre that she was able to do before. Patient is on Carbamazepine, sodium valporate, levetiracetam , salbutamol and Pulmicort inh...

Cowden’s syndrome (CS), also called multiple hamartoma syndrome is an orphan pathology which associates pathognomonic cutaneous-mucosal manifestations with multiple and disseminated hamartomas (skin, mucous membranes, gastrointestinal tract, thyroid, breasts and genitourinary system) and an increased risk of the development of certain malignant tumors, in particular breast, thyroid and endometrial tumors, which are very serious.Observation<p cla...

We are reporting a 33 years old female, known case of primary adrenal failure who presented to our emergency department feeling generally unwell, lethargic and short of breath, She found to be hypothermic, hypotensive and hypoglycaemic. ECG showed low voltage QRS complex with prolonged QT intervals and ECHO confirmed moderate to severe left ventricular dysfunction with features of ’broken heart’ and ballooning suggestive of Takusobo cardiomyopathy. In our case report...

A 64-year-old woman presented acutely with dry cough, difficulty in eating, diarrhoea and weight loss. Her past medical history included cervical carcinoma in situ treated with laser therapy. She was found to be hypercalcaemic, with a corrected calcium of 2.84 mmol/l. During admission, the calcium ranged between 2.8-3.87 mmol/l. The PTH ranged between 0.2-0.4 pmol/l (1.3-9.3 pmol/l). She had raised inflammatory markers and deranged liver function tests. On review, she...

Background: Granulomatous mastitis (GM) is a rare inflammatory condition of the breast typically affecting women during postpartum period. GM can mimic inflammatory breast cancer and only be reliably distinguished through histopathology. While there is no generally accepted treatment for GM, therapeutic options include - antibiotics, wide surgical excision, and corticosteroids.Clinical Case: A 54-year-old female presented to her family physician with wit...